Isaac's work centers around questions of relationship and community, often using portraiture as the means to examine his own communities. Having experienced death and suffering at a young age, the fragility of relationships continues to fascinate him; there is a daily strain between our desire for intimacy and our thinly veiled fear of vulnerability. The tension between life and death—temporal and eternal—continually pushes him to draw back the curtain on our own fears and insecurities.